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Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions

Mesenchymal stromal cells are an important component of the bone marrow hematopoietic niche. Prior studies showed that signaling from members of the transforming growth factor (TGF) superfamily in mesenchymal stromal cells is required for normal niche development. Here, we assessed the impact of TGF...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Krambs, Joseph Ryan, Abou Ezzi, Grazia, Yao, Juo-Chin, Link, Daniel C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259882/
https://ncbi.nlm.nih.gov/pubmed/32470079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233751
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