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Iatrogenic Cushing syndrome and multifocal osteonecrosis caused by the interaction between inhaled fluticasone and ritonavir

Inhaled corticosteroids are generally considered safe and do not usually lead to systemic adverse events since their plasma concentrations are low due to hepatic metabolism by the cytochrome P450 3A4. However, when associated with inhibitors of this cytochrome, such as ritonavir, they may lead to ia...

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Detalhes bibliográficos
Publicado no:BMJ Case Rep
Main Authors: Figueiredo, Joana, Serrado, Margarida, Khmelinskii, Nikita, do Vale, Sónia
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259854/
https://ncbi.nlm.nih.gov/pubmed/32467117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2019-233712
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