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Iatrogenic Cushing's syndrome and osteoporosis due to an interaction between fluticasone and ritonavir

The advent of highly active antiretroviral therapy for HIV infection dramatically changed the landscape of the disease. Ritonavir, a protease inhibitor (PI) frequently used in low doses to ‘boost’ the concentrations of other PIs, inhibits the cytochrome P450 3A4 isoenzyme, a common metabolic pathway...

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Detalles Bibliográficos
Publicado en:BMJ Case Rep
Autores principales: Azevedo, Luísa, Pêgo, Hugo, Souto Moura, Teresa, Germano, Isabel
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636689/
https://ncbi.nlm.nih.gov/pubmed/26516245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2015-211080
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