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Iatrogenic Cushing's syndrome and osteoporosis due to an interaction between fluticasone and ritonavir

The advent of highly active antiretroviral therapy for HIV infection dramatically changed the landscape of the disease. Ritonavir, a protease inhibitor (PI) frequently used in low doses to ‘boost’ the concentrations of other PIs, inhibits the cytochrome P450 3A4 isoenzyme, a common metabolic pathway...

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Библиографические подробности
Опубликовано в: :BMJ Case Rep
Главные авторы: Azevedo, Luísa, Pêgo, Hugo, Souto Moura, Teresa, Germano, Isabel
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636689/
https://ncbi.nlm.nih.gov/pubmed/26516245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr-2015-211080
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