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Iatrogenic Cushing syndrome and adrenal insufficiency during concomitant therapy with ritonavir and fluticasone

Ritonavir is a potent inhibitor of the cytochrome P450 enzyme CYP3A4 and is subject to multiple drug–drug interactions. This becomes especially important when the patient is also taking medications metabolized through CYP3A pathway as increased and potentially toxic drug levels may ensue. Herein we...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Epperla, Narendranath, McKiernan, Fergus
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549367/
https://ncbi.nlm.nih.gov/pubmed/26322261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1218-x
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