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Iatrogenic Cushing syndrome and adrenal insufficiency during concomitant therapy with ritonavir and fluticasone

Ritonavir is a potent inhibitor of the cytochrome P450 enzyme CYP3A4 and is subject to multiple drug–drug interactions. This becomes especially important when the patient is also taking medications metabolized through CYP3A pathway as increased and potentially toxic drug levels may ensue. Herein we...

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Bibliografski detalji
Izdano u:Springerplus
Glavni autori: Epperla, Narendranath, McKiernan, Fergus
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549367/
https://ncbi.nlm.nih.gov/pubmed/26322261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1218-x
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