Alternative splicing of jnk1a in zebrafish determines first heart field ventricular cardiomyocyte numbers through modulation of hand2 expression

The planar cell polarity pathway is required for heart development and whilst the functions of most pathway members are known, the roles of the jnk genes in cardiac morphogenesis remain unknown as mouse mutants exhibit functional redundancy, with early embryonic lethality of compound mutants. In thi...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Santos-Ledo, Adrian, Washer, Sam, Dhanaseelan, Tamil, Eley, Lorraine, Alqatani, Ahlam, Chrystal, Paul W., Papoutsi, Tania, Henderson, Deborah J., Chaudhry, Bill
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259801/
https://ncbi.nlm.nih.gov/pubmed/32421721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008782
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