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Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish

Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remains constant throughout life but that onset of fibro...

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Publicat a:Dis Model Mech
Autors principals: Murphy, Lindsay B., Santos-Ledo, Adrian, Dhanaseelan, Tamilvendhan, Eley, Lorraine, Burns, David, Henderson, Deborah J., Chaudhry, Bill
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319546/
https://ncbi.nlm.nih.gov/pubmed/34296752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.049013
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