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Exercise, programmed cell death and exhaustion of cardiomyocyte proliferation in aging zebrafish

Exercise may ameliorate the eventual heart failure inherent in human aging. In this study, we use zebrafish to understand how aging and exercise affect cardiomyocyte turnover and myocardial remodelling. We show that cardiomyocyte proliferation remains constant throughout life but that onset of fibro...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Murphy, Lindsay B., Santos-Ledo, Adrian, Dhanaseelan, Tamilvendhan, Eley, Lorraine, Burns, David, Henderson, Deborah J., Chaudhry, Bill
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319546/
https://ncbi.nlm.nih.gov/pubmed/34296752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.049013
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