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Emergence of prions selectively resistant to combination drug therapy
Prions are unorthodox infectious agents that replicate by templating misfolded conformations of a host-encoded glycoprotein, collectively termed PrP(Sc). Prion diseases are invariably fatal and currently incurable, but oral drugs that can prolong incubation times in prion-infected mice have been dev...
Tallennettuna:
| Julkaisussa: | PLoS Pathog |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7259791/ https://ncbi.nlm.nih.gov/pubmed/32421750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008581 |
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