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Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates

Oligomeric amyloid β (Aβ) is currently considered the most neurotoxic form of the Aβ peptide implicated in Alzheimer’s disease (AD). The molecular structures of the oligomers have remained mostly unknown due to their transient nature. As a result, the molecular mechanisms of interactions between con...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Khorvash, Massih, Blinov, Nick, Ladner-Keay, Carol, Lu, Jie, Silverman, Judith M., Gibbs, Ebrima, Wang, Yu Tian, Kovalenko, Andriy, Wishart, David, Cashman, Neil R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259632/
https://ncbi.nlm.nih.gov/pubmed/32469918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232266
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