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Allograft inflammatory factor-1 in myeloid cells drives autoimmunity in type 1 diabetes

Allograft inflammatory factor-1 (AIF1) is a calcium-responsive cytoplasmic scaffold protein that directs hematopoiesis and immune responses within dendritic cells (DC) and macrophages. Although the role of AIF1 in transplant rejection and rheumatoid arthritis has been explored, little is known about...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Elizondo, Diana M., Brandy, Nailah Z.D., da Silva, Ricardo L., de Moura, Tatiana R., Lipscomb, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259535/
https://ncbi.nlm.nih.gov/pubmed/32434993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136092
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