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Allograft inflammatory factor-1 in myeloid cells drives autoimmunity in type 1 diabetes

Allograft inflammatory factor-1 (AIF1) is a calcium-responsive cytoplasmic scaffold protein that directs hematopoiesis and immune responses within dendritic cells (DC) and macrophages. Although the role of AIF1 in transplant rejection and rheumatoid arthritis has been explored, little is known about...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Elizondo, Diana M., Brandy, Nailah Z.D., da Silva, Ricardo L., de Moura, Tatiana R., Lipscomb, Michael W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259535/
https://ncbi.nlm.nih.gov/pubmed/32434993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.136092
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