Allograft Inflammatory Factor-1 Governs Hematopoietic Stem Cell Differentiation Into cDC1 and Monocyte-Derived Dendritic Cells Through IRF8 and RelB in vitro

The multistep differentiation process from hematopoietic stem cells through common myeloid progenitors into committed dendritic cell (DC) subsets remains to be fully addressed. These studies now show that Allograft Inflammatory Factor-1 (AIF1) is required for differentiation of classical DC type 1 (...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Elizondo, Diana M., Brandy, Nailah Z. D., da Silva, Ricardo L. L., Haddock, Naomi L., Kacsinta, Apollo D., de Moura, Tatiana R., Lipscomb, Michael W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375893/
https://ncbi.nlm.nih.gov/pubmed/30800127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00173
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