Discovering small molecules as Wnt inhibitors that promote heart regeneration and injury repair

There are intense interests in discovering proregenerative medicine leads that can promote cardiac differentiation and regeneration, as well as repair damaged heart tissues. We have combined zebrafish embryo-based screens with cardiomyogenesis assays to discover selective small molecules that modula...

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Publicado en:J Mol Cell Biol
Main Authors: Xie, Shuying, Fu, Wenbin, Yu, Guangju, Hu, Xueli, Lai, Kaa Seng, Peng, Xiangwen, Zhou, Yating, Zhu, Xuejiao, Christov, Plamen, Sawyer, Leah, Ni, Terri T, Sulikowski, Gary A, Yang, Zhongzhou, Lee, Ethan, Zeng, Chunyu, Wang, Wei E, Zhong, Tao P
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259332/
https://ncbi.nlm.nih.gov/pubmed/30925593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz023
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