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Liquid-liquid phase separation drives skin barrier formation

At the body surface, skin’s stratified squamous epithelium is challenged by environmental extremes. The surface of the skin is composed of enucleated, flattened surface squames. They derive from underlying, transcriptionally active keratinocytes that display filaggrin-containing keratohyalin granule...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Quiroz, Felipe Garcia, Fiore, Vincent F., Levorse, John, Polak, Lisa, Wong, Ellen, Pasolli, H. Amalia, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258523/
https://ncbi.nlm.nih.gov/pubmed/32165560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax9554
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