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Mechanics of a multilayer epithelium instruct tumour architecture and function

Loss of normal tissue architecture is a hallmark of oncogenic transformation(1). In developing organisms, tissues architectures are sculpted by mechanical forces during morphogenesis(2). However, the origins and consequences of tissue architecture during tumorigenesis remain elusive. In skin, premal...

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Bibliografski detalji
Izdano u:Nature
Glavni autori: Fiore, Vincent F., Krajnc, Matej, Quiroz, Felipe Garcia, Levorse, John, Pasolli, H. Amalia, Shvartsman, Stanislav Y., Fuchs, Elaine
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7787055/
https://ncbi.nlm.nih.gov/pubmed/32879493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2695-9
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