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Does liquid–liquid phase separation drive peptide folding?

Proline–arginine (PR) dipeptide repeats have been shown to undergo liquid–liquid phase separation and are an example of a growing number of intrinsically disordered proteins that can assemble into membraneless organelles. These structures have been posited as nucleation sites for pathogenic protein...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Chem Sci
Päätekijät: Edun, Dean N., Flanagan, Meredith R., Serrano, Arnaldo L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Royal Society of Chemistry 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179267/
https://ncbi.nlm.nih.gov/pubmed/34164013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04993j
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