HBV X protein-based therapeutic vaccine accelerates viral antigen clearance by mobilizing monocyte infiltration into the liver in HBV carrier mice

BACKGROUND: Hepatitis B virus (HBV) persistently infected about 250 million people worldwide, and a curative treatment remains an unmet medical need. Among many approaches to treat chronic hepatitis B (CHB), therapeutic vaccines have been developed for two decades, but none have yielded promising re...

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Vydáno v:J Biomed Sci
Hlavní autoři: Horng, Jau-Hau, Lin, Wei-Hsiang, Wu, Chang-Ru, Lin, You-Yu, Wu, Li-Ling, Chen, Ding-Shinn, Chen, Pei-Jer
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257178/
https://ncbi.nlm.nih.gov/pubmed/32466788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00662-x
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