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Hepatitis B Virus Nucleocapsid but Not Free Core Antigen Controls Viral Clearance in Mice

We have recently shown that hepatitis B virus (HBV) core antigen (HBcAg) is the major viral factor for HBV clearance using a hydrodynamics-based mouse model. Knockout of HBcAg hampers the development of antiviral immune responses and thus promotes HBV persistence. Here, we further demonstrated that...

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Detalles Bibliográficos
Main Authors: Lin, Yi-Jiun, Wu, Hui-Lin, Chen, Ding-Shinn, Chen, Pei-Jer
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416136/
https://ncbi.nlm.nih.gov/pubmed/22718814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00608-12
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