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Tbx2 mediates dorsal patterning and germ layer suppression through inhibition of BMP/GDF and Activin/Nodal signaling

BACKGROUND: Members of the T-box family of DNA-binding proteins play a prominent role in the differentiation of the three primary germ layers. VegT, Brachyury, and Eomesodermin function as transcriptional activators and, in addition to directly activating the transcription of endoderm- and mesoderm-...

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Detalhes bibliográficos
Publicado no:BMC Mol Cell Biol
Main Authors: Reich, Shoshana, Kayastha, Peter, Teegala, Sushma, Weinstein, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257154/
https://ncbi.nlm.nih.gov/pubmed/32466750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-020-00282-1
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