Pulmonary Silicosis Alters MicroRNA Expression in Rat Lung and miR-411-3p Exerts Anti-fibrotic Effects by Inhibiting MRTF-A/SRF Signaling

To identify potential therapeutic targets for pulmonary fibrosis induced by silica, we studied the effects of this disease on the expression of microRNAs (miRNAs) in the lung. Rattus norvegicus pulmonary silicosis models were used in conjunction with high-throughput screening of lung specimens to co...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Gao, Xuemin, Xu, Dingjie, Li, Shumin, Wei, Zhongqiu, Li, Shifeng, Cai, Wenchen, Mao, Na, Jin, Fuyu, Li, Yaqian, Yi, Xue, Liu, Heliang, Xu, Hong, Yang, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256439/
https://ncbi.nlm.nih.gov/pubmed/32464548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.05.005
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