Ac-SDKP Attenuates Activation of Lung Macrophages and Bone Osteoclasts in Rats Exposed to Silica by Inhibition of TLR4 and RANKL Signaling Pathways

BACKGROUND: Silica-induced inflammatory activation is associated with silicosis and various non-respiratory conditions. The present study was designed to examine the anti-inflammatory effects of N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) on lung macrophages and bone osteoclasts after silica inh...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Jin, Fuyu, Geng, Fei, Xu, Dingjie, Li, Yaqian, Li, Tian, Yang, Xinyu, Liu, Shupeng, Zhang, Hui, Wei, Zhongqiu, Li, Shifeng, Gao, Xuemin, Cai, Wenchen, Mao, Na, Yi, Xue, Liu, Heliang, Sun, Ying, Yang, Fang, Xu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088302/
https://ncbi.nlm.nih.gov/pubmed/33948088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S306883
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