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Cancer spectrum and outcomes in the Mendelian short telomere syndromes

Short telomeres have been linked to cancer risk, yet other evidence supports them being tumor suppressive. Here, we report cancer outcomes in individuals with germline mutations in telomerase and other telomere-maintenance genes. Among 180 individuals evaluated in a hospital-based setting, 12.8% had...

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Vydáno v:Blood
Hlavní autoři: Schratz, Kristen E., Haley, Lisa, Danoff, Sonye K., Blackford, Amanda L., DeZern, Amy E., Gocke, Christopher D., Duffield, Amy S., Armanios, Mary
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256360/
https://ncbi.nlm.nih.gov/pubmed/32076714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003264
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