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Cancer and Myeloid Clonal Evolution in the Short Telomere Syndromes

The short telomere syndromes are the most common premature aging disorders. Although studies in genetically modified cells and animal models have suggested telomere dysfunction may promote genome instability, only a minority of humans with inherited loss-of-function mutations in telomerase and relat...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Main Authors: Schratz, Kristen E., Armanios, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122241/
https://ncbi.nlm.nih.gov/pubmed/32276199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2020.02.019
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