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Cancer spectrum and outcomes in the Mendelian short telomere syndromes

Short telomeres have been linked to cancer risk, yet other evidence supports them being tumor suppressive. Here, we report cancer outcomes in individuals with germline mutations in telomerase and other telomere-maintenance genes. Among 180 individuals evaluated in a hospital-based setting, 12.8% had...

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Publicado en:Blood
Main Authors: Schratz, Kristen E., Haley, Lisa, Danoff, Sonye K., Blackford, Amanda L., DeZern, Amy E., Gocke, Christopher D., Duffield, Amy S., Armanios, Mary
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256360/
https://ncbi.nlm.nih.gov/pubmed/32076714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003264
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