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Coordination of Rheb lysosomal membrane interactions with mTORC1 activation

A complex molecular machinery converges on the surface of lysosomes to ensure that the growth-promoting signaling mediated by mechanistic target of rapamycin complex 1 (mTORC1) is tightly controlled by the availability of nutrients and growth factors. The final step in this activation process is dep...

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Publicat a:F1000Res
Autors principals: Angarola, Brittany, Ferguson, Shawn M.
Format: Artigo
Idioma:Inglês
Publicat: F1000 Research Limited 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255682/
https://ncbi.nlm.nih.gov/pubmed/32518628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.22367.1
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