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Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition
The mRNA cap‐binding oncoprotein “eIF4E” is phosphorylated at residue S209 by Mnk kinases, and is closely associated with tumor development and progression. Despite being well‐established, mechanistic details at the molecular level of mRNA recognition by eIF4E due to phosphorylation have not been cl...
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| Опубликовано в: : | Protein Sci |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley & Sons, Inc.
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255503/ https://ncbi.nlm.nih.gov/pubmed/31811670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3798 |
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