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Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition

The mRNA cap‐binding oncoprotein “eIF4E” is phosphorylated at residue S209 by Mnk kinases, and is closely associated with tumor development and progression. Despite being well‐established, mechanistic details at the molecular level of mRNA recognition by eIF4E due to phosphorylation have not been cl...

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Библиографические подробности
Опубликовано в: :Protein Sci
Главные авторы: Lama, Dilraj, Verma, Chandra S.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255503/
https://ncbi.nlm.nih.gov/pubmed/31811670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3798
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