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Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition

The mRNA cap‐binding oncoprotein “eIF4E” is phosphorylated at residue S209 by Mnk kinases, and is closely associated with tumor development and progression. Despite being well‐established, mechanistic details at the molecular level of mRNA recognition by eIF4E due to phosphorylation have not been cl...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Lama, Dilraj, Verma, Chandra S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255503/
https://ncbi.nlm.nih.gov/pubmed/31811670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3798
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