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Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition

The mRNA cap‐binding oncoprotein “eIF4E” is phosphorylated at residue S209 by Mnk kinases, and is closely associated with tumor development and progression. Despite being well‐established, mechanistic details at the molecular level of mRNA recognition by eIF4E due to phosphorylation have not been cl...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Lama, Dilraj, Verma, Chandra S.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255503/
https://ncbi.nlm.nih.gov/pubmed/31811670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3798
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