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Deciphering the mechanistic effects of eIF4E phosphorylation on mRNA‐cap recognition

The mRNA cap‐binding oncoprotein “eIF4E” is phosphorylated at residue S209 by Mnk kinases, and is closely associated with tumor development and progression. Despite being well‐established, mechanistic details at the molecular level of mRNA recognition by eIF4E due to phosphorylation have not been cl...

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書目詳細資料
發表在:Protein Sci
Main Authors: Lama, Dilraj, Verma, Chandra S.
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Inc. 2019
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255503/
https://ncbi.nlm.nih.gov/pubmed/31811670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3798
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