Loss of PDK4 expression promotes proliferation, tumorigenicity, motility and invasion of hepatocellular carcinoma cells

Although the roles and underlying mechanisms of other PDK family members (i.e., PDK1, PDK2 and PDK3) in tumor progression have been extensively investigated and are well understood, the functions and underlying molecular mechanisms of pyruvate dehydrogenase kinase 4 (PDK4) in the tumorigenesis and p...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Cancer
Autori principali: Qin, Yu-Juan, Lin, Tao-Yan, Lin, Xiao-Lin, Liu, Yu, Zhao, Wen-Tao, Li, Xiao-Yan, Lian, Mei, Chen, Heng-Wei, Li, Yong-Long, Zhang, Xiao-Ling, Xiao, Dong, Jia, Jun-Shuang, Sun, Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255379/
https://ncbi.nlm.nih.gov/pubmed/32489458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.43459
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