Loss of PDK4 expression promotes proliferation, tumorigenicity, motility and invasion of hepatocellular carcinoma cells

Although the roles and underlying mechanisms of other PDK family members (i.e., PDK1, PDK2 and PDK3) in tumor progression have been extensively investigated and are well understood, the functions and underlying molecular mechanisms of pyruvate dehydrogenase kinase 4 (PDK4) in the tumorigenesis and p...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Qin, Yu-Juan, Lin, Tao-Yan, Lin, Xiao-Lin, Liu, Yu, Zhao, Wen-Tao, Li, Xiao-Yan, Lian, Mei, Chen, Heng-Wei, Li, Yong-Long, Zhang, Xiao-Ling, Xiao, Dong, Jia, Jun-Shuang, Sun, Yan
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255379/
https://ncbi.nlm.nih.gov/pubmed/32489458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.43459
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