The deubiquitinating enzyme UCHL1 promotes resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase

Rationale: Resistance to pemetrexed (PEM)-based chemotherapy is a major cause of progression in non-small cell lung cancer (NSCLC) patients. The deubiquitinating enzyme UCHL1 was recently found to play important roles in chemoresistance and tumor progression. However, the potential roles and mechani...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Theranostics
Päätekijät: Ding, Xinyuan, Gu, Yuting, Jin, Min, Guo, Xin, Xue, Sudong, Tan, Caihong, Huang, Jiefang, Yang, Wanlin, Xue, Mingxing, Zhou, Qianjun, Wang, Wenjuan, Zhang, Yanyun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2020
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255002/
https://ncbi.nlm.nih.gov/pubmed/32483437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.42096
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