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The deubiquitinating enzyme UCHL1 negatively regulates the immunosuppressive capacity and survival of multipotent mesenchymal stromal cells

It is known that proinflammatory cytokines empower multipotent mesenchymal stromal cells (MSCs) the immunosuppressive capacity to treat various inflammatory diseases. Nevertheless, how the proinflammatory cytokines modulate the immunosuppressive capacity of MSCs is poorly understood. In the present...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Gu, Yuting, Ding, Xinyuan, Huang, Jiefang, Xue, Mingxing, Zhang, Jie, Wang, Qiwei, Yu, Hongshuang, Wang, Yanan, Zhao, Fang, Wang, Hui, Jin, Min, Wu, Yeming, Zhang, Yanyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913136/
https://ncbi.nlm.nih.gov/pubmed/29686406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0532-y
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