Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma

BACKGROUND: There is increasing evidence for the benefit of poly ADP ribose polymerase (PARP) inhibitors in a subset of high-grade serous ovarian carcinoma (HGSC) patients, especially those with homologous recombination (HR)-deficient tumors. However, new treatment strategies, such as immune checkpo...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Immunother Cancer
Asıl Yazarlar: Matsushita, Hirokazu, Hasegawa, Kosei, Oda, Katsutoshi, Yamamoto, Shogo, Asada, Kayo, Karasaki, Takahiro, Yabuno, Akira, Nishijima, Akira, Nejo, Takahide, Kobayashi, Yukari, Sato, Sho, Ikeda, Yuji, Miyai, Manami, Takahashi, Yusuke, Yamaguchi, Rui, Fujiwara, Keiichi, Aburatani, Hiroyuki, Kakimi, Kazuhiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2020
Konular:
Basic Tumor Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254153/
https://ncbi.nlm.nih.gov/pubmed/32461346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000375
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller