P04.14 Multiomics analysis on primary and recurrent paired tumors reveals a possible immune evasion mechanism through reduced neoantigen expression in some glioma

BACKGROUND: Limited success of immune-based therapies in glioma might be in part due to the lack of enough neoantigens (neoAgs) that can be targeted by immune effector cells. In addition, gliomas also show dynamic clonal evolution over time, possibly leading to immunoediting during progression. Here...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Nejo, T, Matsushita, H, Karasaki, T, Nomura, M, Takayanagi, S, Tanaka, S, Mukasa, A, Kakimi, K, Saito, N
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
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Poster Presentations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144752/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.248
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