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P04.14 Multiomics analysis on primary and recurrent paired tumors reveals a possible immune evasion mechanism through reduced neoantigen expression in some glioma
BACKGROUND: Limited success of immune-based therapies in glioma might be in part due to the lack of enough neoantigens (neoAgs) that can be targeted by immune effector cells. In addition, gliomas also show dynamic clonal evolution over time, possibly leading to immunoediting during progression. Here...
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| Veröffentlicht in: | Neuro Oncol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144752/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.248 |
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