Muscarinic Toxin 7 Signals Via Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration

Mitochondrial dysfunction is implicated in a variety of neurodegenerative diseases of the nervous system. Peroxisome proliferator–activated receptor-γ coactivator-1α (PGC-1α) is a regulator of mitochondrial function in multiple cell types. In sensory neurons, AMP-activated protein kinase (AMPK) augm...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Saleh, Ali, Sabbir, Mohammad Golam, Aghanoori, Mohamad-Reza, Smith, Darrell R., Roy Chowdhury, Subir K., Tessler, Lori, Brown, Jennifer, Gedarevich, Eva, Kassahun, Markos Z., Frizzi, Katie, Calcutt, Nigel A., Fernyhough, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253379/
https://ncbi.nlm.nih.gov/pubmed/32198698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-01900-x
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