Dysfunctional CD8+ T cells form a proliferative, dynamically regulated compartment within human melanoma

Tumor immune cell compositions play a major role in response to immunotherapy but the heterogeneity and dynamics of immune infiltrates in human cancer lesions remain poorly characterized. Here we identify conserved intratumoral CD4 and CD8 T cell behaviors in scRNA-seq data from 25 melanoma patients...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Li, Hanjie, van der Leun, Anne, Yofe, Ido, Lubling, Yaniv, Solodkin, Dikla Gelbard, van Akkooi, Alexander, van den Braber, Marlous, Rozeman, Lisette, Haanen, John, Blank, Christian, Horlings, Hugo M., David, Eyal, Baran, Yael, Bercovich, Akhiad, Lifshitz, Aviezer, Schumacher, Ton N., Tanay, Amos, Amit, Ido
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253294/
https://ncbi.nlm.nih.gov/pubmed/30595452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.043
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak