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MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions
scRNA-seq profiles each represent a highly partial sample of mRNA molecules from a unique cell that can never be resampled, and robust analysis must separate the sampling effect from biological variance. We describe a methodology for partitioning scRNA-seq datasets into metacells: disjoint and homog...
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| Publicado no: | Genome Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6790056/ https://ncbi.nlm.nih.gov/pubmed/31604482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1812-2 |
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