CRISPRi-mediated functional analysis of lung disease-associated loci at non-coding regions

Genome-wide association studies have identified lung disease-associated loci; however, the functions of such loci are not well understood in part because the majority of such loci are located at non-coding regions. Hi-C, ChIP-seq and eQTL data predict potential roles (e.g. enhancer) of such loci; ho...

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Publicat a:NAR Genom Bioinform
Autors principals: Stuart, William D, Guo, Minzhe, Fink-Baldauf, Iris M, Coleman, Alan M, Clancy, John P, Mall, Marcus A, Lim, Foong-Yen, Brewington, John J, Maeda, Yutaka
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252574/
https://ncbi.nlm.nih.gov/pubmed/32500120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa036
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