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Intratracheal aerosolization of viral vectors to newborn pig airways

Gene therapy for airway diseases requires efficient delivery of nucleic acids to the airways. In small animal models, gene delivery reagents are commonly delivered as a bolus dose. However, large animal models are often more relevant for the transition from preclinical studies to human trials. Aeros...

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Detalles Bibliográficos
Publicado en:Biotechniques
Main Authors: Cooney, Ashley L, Sinn, Patrick L
Formato: Artigo
Idioma:Inglês
Publicado: Future Science Ltd 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7252491/
https://ncbi.nlm.nih.gov/pubmed/32141776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/btn-2019-0150
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