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Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus

Cystic fibrosis (CF) is a common genetic disease caused by mutations in the gene coding for cystic fibrosis transmembrane conductance regulator (CFTR). Although CF affects multiple organ systems, chronic bacterial infections and inflammation in the lung are the leading causes of morbidity and mortal...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Cooney, Ashley L, Singh, Brajesh K, Loza, Laura Marquez, Thornell, Ian M, Hippee, Camilla E, Powers, Linda S, Ostedgaard, Lynda S, Meyerholz, David K, Wohlford-Lenane, Chris, Stoltz, David A, B. McCray, Paul, Sinn, Patrick L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182177/
https://ncbi.nlm.nih.gov/pubmed/30165523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky773
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