Potent antiviral HIV-1 protease inhibitor combats highly drug resistant mutant PR20

Ítems similars

• Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PR(S17)
  per: Agniswamy, Johnson, et al.
  Publicat: (2021)
• Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20
  per: Agniswamy, Johnson, et al.
  Publicat: (2015)
• Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1′-pyrrolidinone ring
  per: Chang, Yu Chung E., et al.
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• Design, Synthesis, and X-ray Structure of Substituted Bis-tetrahydrofuran (Bis-THF)-Derived Potent HIV-1 Protease Inhibitors
  per: Ghosh, Arun K., et al.
  Publicat: (2011)
• Substituent effects on P2-cyclopentyltetrahydrofuranyl urethanes: Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors
  per: Ghosh, Arun K., et al.
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