Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase

Following traumatic insult and associated pathogen infection, innate immunity is activated during the perioperative period, especially the NLRP3 inflammasome in macrophages. The neuroendocrine response is also rapidly activated to regulate excessive inflammation; however, the molecular mechanisms ar...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mediators Inflamm
Main Authors: Wu, Ling, Zhou, Chengfu, Wu, Jianfeng, Chen, Shikun, Tian, Zedan, Du, Quan
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251469/
https://ncbi.nlm.nih.gov/pubmed/32508525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6959741
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