Homogeneous MMR Deficiency Throughout the Entire Tumor Mass Occurs in a Subset of Colorectal Neuroendocrine Carcinomas

Neuroendocrine neoplasms comprise a heterogeneous group of tumors, categorized into neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) depending on tumor differentiation. NECs and high-grade NETs (G3) confer a poor prognosis, demanding novel treatment strategies such as immune checkpo...

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Gepubliceerd in:Endocr Pathol
Hoofdauteurs: Fraune, Christoph, Simon, Ronald, Hube-Magg, Claudia, Makrypidi-Fraune, Georgia, Kluth, Martina, Büscheck, Franziska, Amin, Tania, Viol, Fabrice, Fehrle, Wilfrid, Dum, David, Höflmayer, Doris, Burandt, Eike, Clauditz, Till Sebastian, Perez, Daniel, Izbicki, Jakob, Wilczak, Waldemar, Sauter, Guido, Steurer, Stefan, Schrader, Jörg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250944/
https://ncbi.nlm.nih.gov/pubmed/32144630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12022-020-09612-7
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