Expression of the immune checkpoint receptor TIGIT in seminoma

A characteristic feature of testicular seminoma is the abundance of immune cells in the tumor microenvironment, raising the possibility that immune checkpoint inhibitors may serve as a therapeutic option in these types of tumors. T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitor...

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Published in:Oncol Lett
Main Authors: Hinsch, Andrea, Blessin, Niclas C., Simon, Ronald, Kluth, Martina, Fischer, Kristine, Hube-Magg, Claudia, Li, Wenchao, Makrypidi-Fraune, Georgia, Wellge, Björn, Mandelkow, Tim, Debatin, Nicolaus F., Höflmayer, Doris, Lennartz, Maximilian, Sauter, Guido, Izbicki, Jakob R., Minner, Sarah, Büscheck, Franziska, Uhlig, Ria, Dum, David, Krech, Till, Luebke, Andreas M., Wittmer, Corinna, Jacobsen, Frank, Burandt, Eike, Steurer, Stefan, Wilczak, Waldemar
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2019
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607271/
https://ncbi.nlm.nih.gov/pubmed/31423216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10428
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