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Expression of the immune checkpoint receptor TIGIT in seminoma

A characteristic feature of testicular seminoma is the abundance of immune cells in the tumor microenvironment, raising the possibility that immune checkpoint inhibitors may serve as a therapeutic option in these types of tumors. T cell immunoreceptor with Ig and ITIM domains (TIGIT) is an inhibitor...

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Vydáno v:Oncol Lett
Hlavní autoři: Hinsch, Andrea, Blessin, Niclas C., Simon, Ronald, Kluth, Martina, Fischer, Kristine, Hube-Magg, Claudia, Li, Wenchao, Makrypidi-Fraune, Georgia, Wellge, Björn, Mandelkow, Tim, Debatin, Nicolaus F., Höflmayer, Doris, Lennartz, Maximilian, Sauter, Guido, Izbicki, Jakob R., Minner, Sarah, Büscheck, Franziska, Uhlig, Ria, Dum, David, Krech, Till, Luebke, Andreas M., Wittmer, Corinna, Jacobsen, Frank, Burandt, Eike, Steurer, Stefan, Wilczak, Waldemar
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607271/
https://ncbi.nlm.nih.gov/pubmed/31423216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10428
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