Regulation of the small GTPase Ran by miR-802 modulates proliferation and metastasis in colorectal cancer cells

BACKGROUND: The small GTPase Ran is upregulated in multiple cancers and fundamental for cancer cell survival and progression, but its significance and molecular mechanisms in colorectal cancer (CRC) remain elusive. METHODS: Ran expression was detected in CRC cell lines and tumour tissues. In vitro a...

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Publicat a:Br J Cancer
Autors principals: Wang, Xin, Li, Danxiu, Sun, Lina, Shen, Gaofei, Liu, Hao, Guo, Hao, Ge, Minghui, Liang, Junrong, Chen, Ping, Zhou, Jinchi, Cao, Tianyu, Wang, Qi, Gao, Xiaoliang, Tong, Mingfu, Hu, Sijun, Nie, Yongzhan, Fan, Daiming, wang, xin, Zhao, Xiaodi, Lu, Yuanyuan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250854/
https://ncbi.nlm.nih.gov/pubmed/32210368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0809-7
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