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Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the expression of AR and CXCR4

Ran, a member of the RasGTPase family, has been showed to function in diverse cellular processes of cancer. In the present study, we examined the effects of Ran on the cell motility in pancreatic cancer cells and explored the possible mechanism of Ran’s function in the metastasis of pancreatic cance...

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Bibliographic Details
Main Authors: Deng, Lin, Shang, Yulong, Guo, Shikong, Liu, Changhao, Zhou, Lin, Sun, Yi, Nie, Yongzhan, Fan, Daiming, Lu, Yuanyuan, Guo, Xuegang
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119076/
https://ncbi.nlm.nih.gov/pubmed/24840182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29217
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