Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need

Although sleep is one of the most conserved behaviors, the intracellular mechanism regulating sleep/wakefulness remains unknown. We recently identified a protein kinase, SIK3, as a sleep-regulating molecule. Mice that lack a well-conserved protein kinase A (PKA) phosphorylation site, S551, showed lo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Park, Minjeong, Miyoshi, Chika, Fujiyama, Tomoyuki, Kakizaki, Miyo, Ikkyu, Aya, Honda, Takato, Choi, Jinhwan, Asano, Fuyuki, Mizuno, Seiya, Takahashi, Satoru, Yanagisawa, Masashi, Funato, Hiromasa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250853/
https://ncbi.nlm.nih.gov/pubmed/32457359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65647-0
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak