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Spatiotemporal Control of CRISPR/Cas9 Function in Cells and Zebrafish using Light-Activated Guide RNA
[Image: see text] A light-activated gRNA allows for precise spatiotemporal control of gene editing in both mammalian cells and zebrafish embryos, with excellent off to on switching. This highly programmable approach can be easily adapted to any desired target sequence and can be delivered to a varie...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7250724/ https://ncbi.nlm.nih.gov/pubmed/32160370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201914575 |
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