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Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration

The sox2 expressing (sox2(+)) progenitors in adult mammalian inner ear lose the capacity to regenerate while progenitors in the zebrafish lateral line are able to proliferate and regenerate damaged HCs throughout lifetime. To mimic the HC damage in mammals, we have established a zebrafish severe inj...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Ye, Zhian, Su, Zhongwu, Xie, Siyu, Liu, Yuye, Wang, Yongqiang, Xu, Xi, Zheng, Yiqing, Zhao, Meng, Jiang, Linjia
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7250571/
https://ncbi.nlm.nih.gov/pubmed/32352377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55771
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